Research

The research activities of S2CB lie at the intersection of organic chemistry, polymer science, and colloidal characterization, with a central focus on creating amphiphilic molecular tools for demanding biological applications (axe 1).


We design next-generation detergents (Theme 1), amphiphilic polymers (Theme 2), and detergent-free nanodiscs (Theme 3) to advance the extraction, stabilization, and structural analysis of membrane proteins.


Our work also includes the development of bio-sourced amphiphiles and green polymers (axe 2), incorporating eco-responsible synthetic strategies such as microwave-assisted reactions, green solvents, and low-impact purification.


In parallel, we engineer spin-trapping tools (axe 3) to probe radical chemistry, oxidative stress, and antioxidant mechanisms.
Across all themes, we combine rational molecular design, innovative and sustainable chemistry, and multiscale physicochemical characterization to understand how the structure of amphiphiles governs their function.

This multidisciplinary approach enables the creation of high-performance, sustainable, and biologically relevant tools that support membrane-protein biochemistry, redox studies, and emerging applications at the chemistry–biology interface.